ABSTRACT
OBJECTIVE@#To compare the clinical therapeutic effect and the impacts on recurrence rate on chronic spontaneous urticaria (CSU) between the combined treatment of bloodletting therapy and auricular point sticking on the base of xuanfu theory and the oral solution of levocetirizine hydrochloride.@*METHODS@#A total of 86 patients with CSU were randomized into an observation group (43 cases, 1 case dropped off) and a control group (43 cases, 3 cases dropped off). In the observation group, bloodletting therapy at Dazhui (GV 14), Feishu (BL 13), Geshu (BL 17) and Pishu (BL 20) was combined with auricular point sticking at lung (CO14), kidney (CO10), shenmen (TF4) and heart (CO15), etc. This combined treatment was given once every two days. In the control group, the oral solution of levocetirizine hydrochloride was prescribed, 10 mL each time, once daily. The treatment lasted for 4 weeks in the two groups. Before and after treatment, urticaria activity score 7 (UAS7), the score of dermatology life quality index (DLQI) and the levels of serum immune globulin E (IgE), interleukin 4 (IL-4) and interferon γ (IFN-γ) were compared in the patients between the two groups. The clinical therapeutic effect was evaluated in patients of the two groups and the recurrence rate was followed up 4, 8 and 12 weeks after treatment separately.@*RESULTS@#After treatment, the scores of UAS7 and DLQI, as well as the levels of serum IgE and IL-4 were all reduced as compared with those before treatment in the two groups (P<0.05), and the level of serum IFN-γ was increased (P<0.05). The total effective rate was 83.3% (35/42) in the observation group and was 85.0% (34/40) in the control group. There was no statistical significance for the difference in the clinical therapeutic effect between the two groups (P>0.05). Eight and 12 weeks after treatment, the recurrence rates were 21.1% (4/19) and 26.3% (5/19) in the observation group, lower than 55.0% (11/20) and 65.0% (13/20) in the control group, respectively (P<0.05).@*CONCLUSION@#The combined therapy of bloodletting and auricular point sticking on the base of xuanfu theory relieves the clinical symptoms, regulates the levels of serum IgE, IL-4 and IFN-γ and improves the quality of life in the patients with CSU. The clinical therapeutic effect of this combined treatment is similar to the oral solution of levocetirizine hydrochloride. But, the recurrence rate of the combined treatment of bloodletting and auricular point sticking is lower and its long-term curative effect is better.
Subject(s)
Humans , Acupuncture Points , Acupuncture Therapy , Acupuncture, Ear , Bloodletting , Chronic Urticaria , Quality of Life , Treatment OutcomeABSTRACT
<p><b>OBJECTIVE</b>To compare the difference in the clinical therapeutic effects on slow transit constipation (STC) among the combined therapy of acupuncture and herbal medicine, simple use of herbal medicine and simple use of western medication.</p><p><b>METHODS</b>Ninety patients of STC were randomized into three groups, 30 cases in each one. In the combined therapy group, acupuncture was used in combination with the modifiedformula. In the Chinese herbal medicine group, the modifiedformula was adopted. In the western medication group, mosapride citrate capsules were used. The duration of the treatment was 28 days. Before and after treatment, the colonic transit test was applied, the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were selected for assessment. The clinical therapeutic effects were compared among the three groups.</p><p><b>RESULTS</b>The total effective rate was 96.7% (29/30) in the combined therapy group, better than 90.0% (27/30) in the Chinese herbal medicine group and 76.7% (23/30) in the western medication group (<0.05). In each group, before and after treatment, the residual marker amount was reduced apparently in the colonic transit test (all<0.01). After treatment, the residual marker amount in the combined therapy group was less than that in the Chinese herbal medicine group (<0.05) and that in the western medication group (<0.01). The residual marker amount in the Chinese herbal medicine group was less than that in the western medication group (<0.01). Compared with those before treatment, the scores of SAS and SDS were decreased in the combined therapy group and Chinese herbal medicine group (both<0.01). After treatment, the scores of SAS and SDS in the combined therapy group were lower obviously than those in the other two groups (both<0.01).</p><p><b>CONCLUSIONS</b>Under the guidance oftheory, the combination of acupuncture and Chinese herbal medicine improve appa-rently colonic function and relieve the conditions of anxiety and depression in STC patients. The therapeutic effects are better than those treated with simple use of Chinese herbal medicine and simple use of western medication.</p>
ABSTRACT
On the basis of the origin,development and modern research of xuanfu theory,a new view of nose xuanfu theory is put forward,in wich,the mechanism of chronic sinusitis is blodkade of two orrifices and interties of two toxins.Additionally,on the basis of inducing resuscitation and opening xuanfu,a new treatment principle of dredging sinus orrifi ces,opening xuanfu,removing two toxins and strengthening vital qi are put forward,too.From modern medical point,nose xuanfu is corresponding to intercellular space of nasal mucous membrane,all kinds of ion channels and nasal tissue microcirculation.Nose xuanfu is qi-fluid circulation channel in internal and external environmental material information communication of nasal tissue.Nose xuanfu normal opening-and-closing function keeps normal physiological function of nasal cavity.Nose xuanfu theory provides one new way in rhinology with TCM.